Diazepam is N-demethylated by CYP3A4 and 2C19 for the Energetic metabolite N-desmethyldiazepam, and is particularly hydroxylated by CYP3A4 for the active metabolite temazepam. N-desmethyldiazepam and temazepam are the two more metabolized to oxazepam. Temazepam and oxazepam are mostly removed by glucuronidation.Normally, your health practitioner wi